GLP-1 (glucagon-like-peptide-1), a receptor agonist
This means that it mimics the hormone GLP-1, which regulates hunger and food intake. Additionally, when GLP-1 is taken on a weekly basis, it suppresses the hormone glucagon to prevent feelings of hunger. Additionally, it delays gastric emptying, therefore making you feel more satisfied after a meal.
GLP-1 injections combined with exercise resulted in a mean decrease in body weight
A recent study of 1,961 people found that in people with a BMI over 30 and who did not have diabetes, GLP-1 injections combined with exercise resulted in a mean decrease in body weight of 14.9% over 68 weeks. The placebo group saw only a 2.4% mean decrease in weight.
GLP-1 provided even more significant weight loss
A second study found that when combined with behavioral therapy and incorporating a low-calorie diet into meal plans, GLP-1 provided even more significant weight loss.GLP-1 is often prescribed to men and women who have a Body Mass Index (BMI) of 30 or higher, or individuals with a BMI of 27 or higher that is accompanied by high blood pressure, type 2 diabetes, high cholesterol, or other health conditions that can make weight loss difficult.