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The Controversy Surrounding TRT
Safety concerns have long surrounded TRT, especially following studies that suggested a possible link between hormone therapy and an increased risk of cardiovascular disease. Dr. Frances Hayes, a reproductive endocrinologist, highlights that many studies had methodological flaws:
- Some used TRT doses much higher than what is typically prescribed.
- Participants were often older and had other health conditions that could skew results.
Current Research Insights
Additionally, a study published in the Mayo Clinic Proceedings showed no correlation between TRT and venous blood clots among nearly 30,000 men. Dr. Hayes summarizes the current stance: “At this point, the impact of TRT on cardiovascular health remains inconclusive.”
Concerns about TRT’s association with prostate cancer have also been challenged. A December 2015 study in the Journal of Urology concluded that exposure to TRT over five years did not correlate with an increased risk of aggressive prostate cancer.
The Long-Term Perspective
While the long-term risks of TRT are still not fully understood, many studies have limited follow-up periods. This does not necessarily mean that TRT should be avoided; for select men, the therapy can be a beneficial option.
Who Is a Good Candidate for TRT?
- Fatigue
- Sexual dysfunction
Even if low levels and symptoms are present, TRT might not be the first recommended course of action. Identifying the underlying cause of declining testosterone levels can often lead to natural increases. For example, weight gain is a primary contributor to decreased testosterone levels. A five-point rise in body mass index (BMI) can equate to a ten-year increase in biological age concerning testosterone levels.
Managing Expectations with TRT
How Is TRT Administered?
Fatigue : Applied daily to areas like the upper arms, shoulders, or thighs. This method offers more stable testosterone levels but requires caution to avoid skin contact with others for several hours due to potential side effects like acne or hair growth.
Injections : Typically given in the buttocks every two weeks. While injections may cause fluctuations in testosterone levels, leading to mood and energy spikes followed by declines.
Re-evaluating TRT
Erectile dysfunction is addressed by physicians through a comprehensive medical checkup and an in-depth discussion of your symptoms. If you are eligible for treatment, a specialist in this area will explore treatment methods with you and oversee your care.